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Variant and Mutation Types
CTL/CD8+ Variant Search
HIV protein
-ALL-
Gag
Pol
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HIV-2 proteins
SIV proteins
HXB2 protein location
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Results overlap with query location
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Results exactly match query location
Epitope or variant sequence
Results contain query sequence
Results exactly match query sequence
Results fuzzy match to query sequence
Epitope record number
Variant record number
Show only this variant
Show all variants for the matching epitope
Mutation type
-ALL-
A: HLA association
AHE: altered HLA expression
AKB: altered KIR binding or increased/decreased off-rate
CE: calculated escape
CHB: calculated diminished HLA binding
CM: compensatory mutation
DHB: diminished HLA binding or increased off-rate
DI: drug induced
DR: diminished response
E: escape documented in this paper
EL: epitope loss
F: replicative capacity/ fitness enhanced
HBOK: HLA binding unchanged
I: insertion
IE: inferred escape
LE: literature escape
NSF: non-susceptible form
OV: observed variant
P: processing
R: reversion
RCOK: replicative capacity is not abrogated
RCR: replicative capacity reduced
SF: susceptible form
SNSF: subtype-specific non-susceptible form
SSF: subtype-specific susceptible form
TCR: TCR related mutation
Show only matching variants
Show all variants for the matching epitopes
Variant method
-ALL-
assay for Class I down-regulation by Nef
CD4 T-cell Elispot - IFNy
CD8 T-cell Elispot granzyme B
CD8 T-cell Elispot - IFNy
Chromium-release assay
Computer prediction
CTL suppression of replication
Cytokine production
Cytolytic LDH release assay
Cytotoxicity assay
Flow cytometric T-cell cytokine assay
HLA binding
HLA stabilization assay
Intracellular cytokine staining
Longitudinal study
Other
Peptide titration
Previously reported in the literature
Proliferation
Relative replication capacity assay
Sequence
Structural prediction
Surface Plasmon Resonance
T-cell Elispot
TCR binding
Tetramer binding
Show only matching variants
Show all variants for the matching epitopes
Restricting MHC/HLA
-ALL-
A*01
A*01:01
A*02
A*02:01
A*02:02
A*02:05
A*02:06
A*02:07
A*03
A*03:01
A1
A*11
A11
A*11:01
A2
A*23
A*23:01
A*24
A24
A*24:02
A*25
A*25:01
A*26
A26
A*26:01
A*26:02
A*26:03
A*29
A29
A*29:02
A3
A*30
A30
A*30:01
A*30:02
A*31:01
A32
A*32:01
A*33
A33
A*33:03
A3 supertype
A*68
A68
A*68:01
A*68:02
A*74
A*74:01
B*07
B*07:02
B*08
B*08:01
B*13
B13
B*13:02
B*14
B14
B*14:01
B*14:02
B*15
B15
B*15:01
B*15:03
B*15:10
B*15:16
B*18
B18
B*18:01
B*27
B27
B*27:05
B*35
B35
B*35:01
B*35:02
B*35:05
B*38
B*38:01
B*39:10
B*40
B40
B*40:01
B*40:02
B*40:06
B*42
B42
B*42:01
B*42:02
B*44
B44
B*44:02
B*44:03
B45
B*45:01
B*48:01
B49
B50
B*51
B51
B*51:01
B52
B*52:01
B*53
B53
B*53:01
B*54:01
B55
B*55:01
B*57
B57
B*57:01
B*57:02
B*57:03
B*58
B58
B*58:01
B*58:02
B60
B*62
B62
B*63
B63
B*67:01
B7
B70
B7 supertype
B8
B*81
B81
B*81:01
C*01
C*01:02
C*03
C*03:03
C*03:04
C*04
C*04:01
C*05
C*06:02
C*07:01
C*07:02
C*08
C*08:02
C*12
C*12:02
C*12:03
C*15:05
Cw3
Cw4
Cw5
Cw7
Cw8
DR1
E*01:01
E*01:03
H2-Dd
H-2Dd
H-2Kd
H-2d
Mamu-A*01
Questions or comments? Contact us at
immuno@lanl.gov