HIV Databases HIV Databases home HIV Databases home
HIV sequence database

Variable Region Characteristics

Purpose: Variable Region Characteristics analyzes protein sequences for V1, V2, V3, V4, V5 lengths, glycosylations, and net charge. For details, see the explanation.

Paste alignment icon

[Sample Input]
Or upload a file
Net charge icon KRH = +, DE = -       KR = +, DE = -
Specify regions icon Select HIV-1 variable regions (for HIV-1 ENV alignment that includes HXB2)
V1: Full loop (130-158)*    Hypervariable region (132-152)
V2: Full loop (157-197)*    Hypervariable region (185-190)
V1+V2: Full loop (130-157 + 158-197)*    Hypervariable region (132-152 + 185-190)
V3: Full loop (295-332)*         (loop not hypervariable)
V4: Full loop (385-418)    Hypervariable region (396-410)
V5: Full loop (459-470)*    Hypervariable region (460-465)
* Results for V1, V2, V3, and V5 include one position immediately before and another immediately after the region so that glycosylation sites at the boundaries are counted.
Use alignment positions to
Use reference positions to
Group summary icon Include summary by grouped sequences according to
    first character(s) in sequence names
the column in field of sequence names delimited by
paste or upload grouped sequence names (see example below)

Email results icon Recommended if you experience a browser timeout
plus Features
last modified: Fri Aug 5 14:38 2022

Questions or comments? Contact us at

Operated by Triad National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
© Copyright Triad National Security, LLC. All Rights Reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health