Purpose: Poisson-Fitter analyzes sets of homogeneous DNA sequences and performs statistical tests on the Hamming Distance frequency distributions. It computes the best fitting Poisson distribution through Maximum Likelihood, performs a Goodness of Fit test, and tests for Star-Phylogeny. See Help.
Note: Poisson-Fitter version 2 was released in May 2015. This new version calculates the standard deviation using U statistics. The older version, Poisson Fitter v1, works for sets of ≤150 sequences and calculates standard deviation by jackknife resampling.
Details: The tool accepts a single input file, which may contain sets of aligned sequences from one or more patients. It also accepts properly-formatted large-scale input. Please read Help file before using the tool!
Reference: Please reference this article when using Poisson Fitter: