A tool for Prediction & Analysis of Neutralization by Antibody Combinations
This tool predicts and analyzes combination antibody neutralization scores using IC50 and/or IC80 for
individual antibodies. The predicted scores are systematically compared for all single antibodies and
2, 3 and 4 antibody combinations analyzed. See explanation.
Kshitij Wagh, Tanmoy Bhattacharya, Carolyn Williamson, Alex Robles, Madeleine Bayne, Jetta Garrity, Michael Rist, Cecilia Rademeyer, Hyejin Yoon, Alan Lapedes, Hongmei Gao, Kelli Greene, Mark K. Louder, Rui Kong, Salim Abdool Karim, Dennis R. Burton, Dan H. Barouch, Michel C. Nussenzweig, John R. Mascola, Lynn Morris, David C. Montefiori, Bette Korber and Michael S. Seaman. Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection. PLoS Pathog. 2016 Mar 30;12(3):e1005520. PubMed.
last modified: Tue Sep 27 15:30 2016