HIV Databases

The HIV databases contain comprehensive data on HIV genetic sequences and immunological epitopes. The website also gives access to a large number of tools that can be used to analyze and visualize these data. This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Interagency Agreement No. AAI12007-001-00000. Our content is reviewed by an Editorial Board.

CATNAP: two new features
CATNAP now provides an option to calculate geometric mean estimates including tests that were above threshold (setting a score of 100 (IC_50/80) or 20 (ID_50/80) for the purpose of the estimation). Also, we have introduced a "Trim-and-Re-calculate" feature in the analysis which enables users to select data from specified papers instead of using the full set in CATNAP collection. This could be useful to reduce data redundancy or to address inconsistencies between studies (for instance, changes in pipette tips used for serial dilution). 20 February 2019

GenSig
GenSig, a signature analysis web interface, is now available online. It can identify genetic signatures in a DNA alignment with associated phenotypic data. Also we have integrated our signature code into CATNAP allowing signature analysis to be conducted on-the-fly as new bNAb data is entered into the database. 10 January 2019

Questions or comments? Contact us at seq-info@lanl.gov