HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54627

HXB2 Location  Gag(24-31)   Gag Epitope Map
View variants at this location
Epitope GGKKKYKL   Epitope Alignment
GGKKKYKf   escape documented in this paper
Epitope Name GL8
Species (MHC/HLA human(B8)

Variant Details

Showing all: 1 variant(s).

Variant ID.  954
Epitope Seq.  GGKKKYKL
Variant Seq.  GGKKKYKf
Mutations L/F
Epitope Location L8F
HXB2 Location L31F
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy
Note Presumed escape variant was transmitted from a B8 positive donor to a B8 negative recipient. The variant was not recognized by CTLs.


Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.

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