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Displaying record number 54627

HXB2 Location Gag(24-31) Gag Epitope Map
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Epitope

GGKKKYKL

Epitope Alignment

Variants

GGKKKYKf escape documented in this paper

Epitope Name GL8

Species (MHC/HLA) human(B8)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`954`
Epitope Seq.	`GGKKKYKL`
Variant Seq.	`GGKKKYKf`
Mutations	L/F
Epitope Location	L8F
HXB2 Location	L31F
Mutation Type	E: escape documented in this paper
Method	CD8 T-cell Elispot - IFNy
Note	Presumed escape variant was transmitted from a B8 positive donor to a B8 negative recipient. The variant was not recognized by CTLs.

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.