HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(197-205) | Gag Epitope Map
View variants at this location |
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| Epitope |
AMQMLKDTI
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | G | |||||
| Species (MHC/HLA) | mouse(H-2Kd) | |||||
Showing 1 of 2 variants.
| Variant ID. | 806 |
|---|---|
| Epitope Seq. | AMQMLKDTI |
| Variant Seq. | AMQiLKDTI |
| Mutations | M/I |
| Epitope Location | M4I |
| HXB2 Location | M200I |
| Mutation Type | DR: diminished response |
| Epitope Subtype | A, C |
| Variant Subtype | B |
| Method | CD8 T-cell Elispot - IFNy |
| Note | After immunization with Clades A or C vaccines, both containing the wt epitope, T cells responded well to the index epitope, and intermediately to this variant. |
Larke2007 Natasha Larke, Eung-Jun Im, Ralf Wagner, Carolyn Williamson, Anna-Lise Williamson, Andrew J. McMichael, and Tomáš Hanke. Combined Single-Clade Candidate HIV-1 Vaccines Induce T Cell Responses Limited by Multiple Forms of In Vivo Immune Interference. Eur. J. Immunol., 37(2):566-577, Feb 2007. PubMed ID: 17230443. Show all entries for this paper.