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Displaying record number 53755

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLfNTVAvL escape documented in this paper

Epitope Name SL9

Species (MHC/HLA) human(A2)

Variant Details

Showing 1 of 6 variants.

Variant ID.	`755`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVAvL`
Mutations	Y/F T/V
Epitope Location	Y3F T8V
HXB2 Location	Y79F T84V
Mutation Type	E: escape documented in this paper
Method	CD8 T-cell Elispot - IFNy, Chromium-release assay
Note	Variant dominated in the middle of a 7 year period in a patient. It was not recognized by patient CTLs.

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.