HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | SL9 | |||||
| Species (MHC/HLA) | human(A*02) | |||||
Showing 1 of 2 variants.
| Variant ID. | 69 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTVAvL |
| Mutations | T/V |
| Epitope Location | T8V |
| HXB2 Location | T84V |
| Mutation Type | SSF: subtype-specific susceptible form |
| Epitope Subtype | B |
| Variant Subtype | A, F |
| Method | Chromium-release assay |
| Note | SL9 epitope variants used were SLYNTVATL for clades B/A1/C/D, SLYNTVAVL for clades A2/F1, and SLFNTVATL for clades G/K. Clade B-elicited CTLs recognized epitopes from all other clades when tested by Cr-release. |
Bennett2008 Michael S. Bennett, Hwee L. Ng, Ayub Ali, and Otto O. Yang. Cross-Clade Detection of HIV-1-Specific Cytotoxic T Lymphocytes Does Not Reflect Cross-Clade Antiviral Activity. J. Infect. Dis., 197(3):390-397, 1 Feb 2008. PubMed ID: 18184090. Show all entries for this paper.