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Found 1 matching record:

Displaying record number 55518

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNTVAvL   subtype-specific susceptible form
Epitope Name SL9
Species (MHC/HLA human(A*02)

Variant Details

Showing 1 of 2 variants.


Variant ID.  69
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTVAvL
Mutations T/V
Epitope Location T8V
HXB2 Location T84V
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype A, F
Method Chromium-release assay
Note SL9 epitope variants used were SLYNTVATL for clades B/A1/C/D, SLYNTVAVL for clades A2/F1, and SLFNTVATL for clades G/K. Clade B-elicited CTLs recognized epitopes from all other clades when tested by Cr-release.

References

Bennett2008 Michael S. Bennett, Hwee L. Ng, Ayub Ali, and Otto O. Yang. Cross-Clade Detection of HIV-1-Specific Cytotoxic T Lymphocytes Does Not Reflect Cross-Clade Antiviral Activity. J. Infect. Dis., 197(3):390-397, 1 Feb 2008. PubMed ID: 18184090. Show all entries for this paper.


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