HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 53745

HXB2 Location  Gag(167-175)   Gag Epitope Map
View variants at this location
Epitope EVIPMFSAL   Epitope Alignment
Variants
kVIPMFSAL   diminished HLA binding or increased off-rate
Species (MHC/HLA human(A*26:01, A*26:03)

Variant Details

Showing 1 of 16 variants.


Variant ID.  685
Epitope Seq.  EVIPMFSAL
Variant Seq.  kVIPMFSAL
Mutations E/K
Epitope Location E1K
HXB2 Location E167K
Mutation Type DHB: diminished HLA binding or increased off-rate
Method CD8 T-cell Elispot - IFNy
Note Variant did not bind to A*2603.

References

Kawashima2005 Yuka Kawashima, Manami Satoh, Shinichi Oka, and Masafumi Takiguchi. Identification and Characterization of HIV-1 Epitopes Presented by HLA-A*2603: Comparison Between HIV-1 Epitopes Presented by A*2601 and A*2603. Hum. Immunol., 66(11):1155-1166, Nov 2005. PubMed ID: 16571416. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health