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Displaying record number 53613

HXB2 Location Gag(141-155) Gag Epitope Map
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Epitope

QMVHQSLSPRTLNAW

Epitope Alignment

Variants

QMVHQaLSPRTLNAW observed variant

Species (MHC/HLA) human

Variant Details

Showing 1 of 2 variants.

Variant ID.	`66`
Epitope Seq.	`QMVHQSLSPRTLNAW`
Variant Seq.	`QMVHQaLSPRTLNAW`
Mutations	S/A
Epitope Location	S6A
HXB2 Location	S146A
Mutation Type	OV: observed variant
Method	CD8 T-cell Elispot - IFNy
Note	The sequence contains a known B7/B8 epitope, but the subjects recognizing it are B7- and B8-negative. The viral sequences isolated from the subjects were qmThqNlsprtlnaw and qmvhqAlsprtlnaw, and the index peptide was recognized.

References

Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.