HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54579

HXB2 Location  Gag(93-101)   Gag Epitope Map
View variants at this location
Epitope EVKDTKEAL   Epitope Alignment
EiKDTKEAL   inferred escape
Epitope Name EL9
Species (MHC/HLA human(B*08)

Variant Details

Showing 1 of 4 variants.

Variant ID.  638
Epitope Seq.  EVKDTKEAL
Variant Seq.  EiKDTKEAL
Mutations V/I
Epitope Location V2I
HXB2 Location V94I
Mutation Type IE: inferred escape
Method CD8 T-cell Elispot - IFNy
Note Author tabulates this variant detected in 9/14 clones at week 39 in patient OP428 as viral escape. No CTL response detected.


Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.

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