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Found 1 matching record:

Displaying record number 54556

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNaiATL   inferred escape
Epitope Name SL9
Species (MHC/HLA human(A*02)

Variant Details

Showing 1 of 4 variants.


Variant ID.  635
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNaiATL
Mutations T/A V/I
Epitope Location T5A V6I
HXB2 Location T81A V82I
Mutation Type IE: inferred escape
Method CD8 T-cell Elispot - IFNy
Note Author tabulates this variant detected in 1/14 clones at week 39 in patients. OP428 as viral escape. No CTL response detected.

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


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