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Found 1 matching record:

Displaying record number 54497

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SvYNTVATL   diminished response; susceptible form
Epitope Name SL9
Species (MHC/HLA human, mouse(A2)

Variant Details

Showing 1 of 29 variants.


Variant ID.  623
Epitope Seq.  SLYNTVATL
Variant Seq.  SvYNTVATL
Mutations L/V
Epitope Location L2V
HXB2 Location L78V
Mutation Type DR: diminished response
SF: susceptible form
Note This variant was recognized by both SL9-CTLs and by the T/A-variant CTLs from this patient, but to somewhat lesser extent than the wt epitope. It was also recognized by SL9- and T/A-CTLs derived from sister cells from another patient.

References

Kan-Mitchell2006 June Kan-Mitchell, Melissa Bajcz, Keri L. Schaubert, David A. Price, Jason M. Brenchley, Tedi E. Asher, Daniel C. Douek, Hwee L. Ng, Otto O. Yang, Charles R. Rinaldo, Jr., Jose Miguel Benito, Brygida Bisikirska, Ramakrishna Hegde, Franco M. Marincola, César Boggiano, Dianne Wilson, Judith Abrams, Sylvie E. Blondelle, and Darcy B. Wilson. Degeneracy and Repertoire of the Human HIV-1 Gag p17(77-85) CTL Response. J. Immunol., 176(11):6690-6701, 1 Jun 2006. PubMed ID: 16709828. Show all entries for this paper.


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