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Displaying record number 54497

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLfNTVAvL diminished response; escape documented in this paper

Epitope Name SL9

Species (MHC/HLA) human, mouse(A2)

Variant Details

Showing 1 of 29 variants.

Variant ID.	`619`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVAvL`
Mutations	Y/F T/V
Epitope Location	Y3F T8V
HXB2 Location	Y79F T84V
Mutation Type	DR: diminished response E: escape documented in this paper
Note	This variant was not recognized by SL9-CTLs from one patient while it was recognized by the T/A-variant CTLs from this patient and by SL9- and T/A-CTLs derived from sister cells from another patient. It was recognized to a lesser extent than the wt.

References

Kan-Mitchell2006 June Kan-Mitchell, Melissa Bajcz, Keri L. Schaubert, David A. Price, Jason M. Brenchley, Tedi E. Asher, Daniel C. Douek, Hwee L. Ng, Otto O. Yang, Charles R. Rinaldo, Jr., Jose Miguel Benito, Brygida Bisikirska, Ramakrishna Hegde, Franco M. Marincola, César Boggiano, Dianne Wilson, Judith Abrams, Sylvie E. Blondelle, and Darcy B. Wilson. Degeneracy and Repertoire of the Human HIV-1 Gag p17(77-85) CTL Response. J. Immunol., 176(11):6690-6701, 1 Jun 2006. PubMed ID: 16709828. Show all entries for this paper.