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Displaying record number 54497

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
lLwNTslaL   susceptible form
Epitope Name SL9
Species (MHC/HLA human, mouse(A2)

Variant Details

Showing 1 of 29 variants.


Variant ID.  612
Epitope Seq.  SLYNTVATL
Variant Seq.  lLwNTslaL
Mutations S/L Y/W V/S A/L T/A
Epitope Location S1L Y3W V6S A7L T8A
HXB2 Location S77L Y79W V82S A83L T84A
Mutation Type SF: susceptible form
Note 74 synthesized SL9 variants were tested for recognition by CTLs from 9 HLA-A2+ donors. This variant was one of the 22 recognized by CTLs. It was recognized by CTLs from 3/8 donors.

References

Kan-Mitchell2006 June Kan-Mitchell, Melissa Bajcz, Keri L. Schaubert, David A. Price, Jason M. Brenchley, Tedi E. Asher, Daniel C. Douek, Hwee L. Ng, Otto O. Yang, Charles R. Rinaldo, Jr., Jose Miguel Benito, Brygida Bisikirska, Ramakrishna Hegde, Franco M. Marincola, César Boggiano, Dianne Wilson, Judith Abrams, Sylvie E. Blondelle, and Darcy B. Wilson. Degeneracy and Repertoire of the Human HIV-1 Gag p17(77-85) CTL Response. J. Immunol., 176(11):6690-6701, 1 Jun 2006. PubMed ID: 16709828. Show all entries for this paper.


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