Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTIATL
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Epitope Alignment | ||||
Variants |
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Epitope Name | SL9 | |||||
Species (MHC/HLA) | human(A*02:01) |
Showing 1 of 2 variants.
Variant ID. | 60 |
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Epitope Seq. | SLYNTIATL |
Variant Seq. | SLYNTIAvL |
Mutations | T/V |
Epitope Location | T8V |
HXB2 Location | T84V |
Mutation Type | SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay, Intracellular cytokine staining |
Note | The response to this variant peptide, SVL9, was not apparent until month 20, by month 32 a T to V change was dominant, but the SLYNTIAvL mutant showed comparable avidity. |
Bansal2005a Anju Bansal, Ethan Gough, Steffanie Sabbaj, Doug Ritter, Karina Yusim, Greg Sfakianos, Grace Aldrovandi, Richard A. Kaslow, Craig M. Wilson, Mark J. Mulligan, J. Michael Kilby, and Paul A. Goepfert. CD8 T-Cell Responses in Early HIV-1 Infection Are Skewed Towards High Entropy Peptides. AIDS, 19(3):241-250, 18 Feb 2005. PubMed ID: 15718834. Show all entries for this paper.
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