HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(77-85)|| Gag Epitope Map
View variants at this location
|Species (MHC/HLA)||human, mouse(A2)|
Showing 1 of 29 variants.
|Mutation Type||SF: susceptible form|
|Note||This synthesized variant was recognized by CTLs from 8/9 individuals. The variant was more immunogenic than the wt, reduced IL-2-mediated activation induced cell death that the wt CTLs were susceptible to, and induced broad response to several SL9 variants.|
Kan-Mitchell2006 June Kan-Mitchell, Melissa Bajcz, Keri L. Schaubert, David A. Price, Jason M. Brenchley, Tedi E. Asher, Daniel C. Douek, Hwee L. Ng, Otto O. Yang, Charles R. Rinaldo, Jr., Jose Miguel Benito, Brygida Bisikirska, Ramakrishna Hegde, Franco M. Marincola, César Boggiano, Dianne Wilson, Judith Abrams, Sylvie E. Blondelle, and Darcy B. Wilson. Degeneracy and Repertoire of the Human HIV-1 Gag p17(77-85) CTL Response. J. Immunol., 176(11):6690-6701, 1 Jun 2006. PubMed ID: 16709828. Show all entries for this paper.