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Found 1 matching record:

Displaying record number 53223

HXB2 Location  Gag(119-127)   Gag Epitope Map
View variants at this location
Epitope AADTGNSSQ   Epitope Alignment
Variants
AADTGNSSk   escape documented in this paper
Epitope Name Gag AQ9
Species (MHC/HLA human

Variant Details

Showing 1 of 16 variants.


Variant ID.  512
Epitope Seq.  AADTGNSSQ
Variant Seq.  AADTGNSSk
Mutations Q/K
Epitope Location Q9K
HXB2 Location Q127K
Mutation Type E: escape documented in this paper
Note Variant dramatically reduced CTL recognition.

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.

Yang2019 Yiding Yang, and Vitaly V. Ganusov. Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection. Microorganisms, 7(3):microorganisms7030069 doi, Mar 2019. PubMed ID: 30836625 Show all entries for this paper.


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