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Displaying record number 53223

HXB2 Location Gag(119-127) Gag Epitope Map
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Epitope

AADTGNSSQ

Epitope Alignment

Variants

eADTGkSSQ escape documented in this paper

Epitope Name Gag AQ9

Species (MHC/HLA) human

Variant Details

Showing 1 of 16 variants.

Variant ID.	`511`
Epitope Seq.	`AADTGNSSQ`
Variant Seq.	`eADTGkSSQ`
Mutations	A/E N/K
Epitope Location	A1E N6K
HXB2 Location	A119E N124K
Mutation Type	E: escape documented in this paper
Note	Variant dramatically reduced CTL recognition.

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.

Yang2019 Yiding Yang, and Vitaly V. Ganusov. Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection. Microorganisms, 7(3):microorganisms7030069 doi, Mar 2019. PubMed ID: 30836625 Show all entries for this paper.