HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 62254

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
KIqLRPGGK   susceptible form
Species (MHC/HLA human(A*03)

Variant Details

Showing 1 of 5 variants.

Variant ID.  4372
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIqLRPGGK
Mutations R/Q
Epitope Location R3Q
HXB2 Location R20Q
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIqLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.

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