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Found 1 matching record:

Displaying record number 62220

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNTML   Epitope Alignment
Variants
TPsDLNTML   observed variant
Epitope Name Gag-TL9
Species (MHC/HLA human(B*42:01)

Variant Details

Showing 1 of 3 variants.


Variant ID.  4349
Epitope Seq.  TPQDLNTML
Variant Seq.  TPsDLNTML
Mutations Q/S
Epitope Location Q3S
HXB2 Location Q182S
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Other
Note TPsDLNTML (Q182S) was observed in B*8101+ (which is a restricting HLA for TL9) subject K-3046-C at age 7.8. K-3046-C was a subject in the Pediatric Early HAART and Strategic Treatment Interruption Study.

References

Leitman2017 Ellen M. Leitman, Christina F. Thobakgale, Emily Adland, M. Azim Ansari, Jayna Raghwani, Andrew J. Prendergast, Gareth Tudor-Williams, Photini Kiepiela, Joris Hemelaar, Jacqui Brener, Ming-Han Tsai, Masahiko Mori, Lynn Riddell, Graz Luzzi, Pieter Jooste, Thumbi Ndung'u, Bruce D. Walker, Oliver G. Pybus, Paul Kellam, Vivek Naranbhai, Philippa C. Matthews, Astrid Gall, and Philip J. R. Goulder. Role of HIV-Specific CD8+ T Cells in Pediatric HIV Cure Strategies after Widespread Early Viral Escape. J. Exp. Med., 214(11):3239-3261, 6 Nov 2017. PubMed ID: 28983013. Show all entries for this paper.


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