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Displaying record number 62140

HXB2 Location Gag(209-223) Gag Epitope Map
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Epitope

AAEWDRLHPVHAGPI

Epitope Alignment

Variants

AAEWDRvHPVHAGPI susceptible form

Epitope Name MOS-219

Species (MHC/HLA) human

Variant Details

Showing all: 1 variant(s).

Variant ID.	`4210`
Epitope Seq.	`AAEWDRLHPVHAGPI`
Variant Seq.	`AAEWDRvHPVHAGPI`
Mutations	L/V
Epitope Location	L7V
HXB2 Location	L215V
Mutation Type	SF: susceptible form
Method	Chromium-release assay, Intracellular cytokine staining, Other
Note	This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-20, and is recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.