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Found 1 matching record:

Displaying record number 62140

HXB2 Location  Gag(209-223)   Gag Epitope Map
View variants at this location
Epitope AAEWDRLHPVHAGPI   Epitope Alignment
Variants
AAEWDRvHPVHAGPI   susceptible form
Epitope Name MOS-219
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4210
Epitope Seq.  AAEWDRLHPVHAGPI
Variant Seq.  AAEWDRvHPVHAGPI
Mutations L/V
Epitope Location L7V
HXB2 Location L215V
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-20, and is recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


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