HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


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Displaying record number 62101

HXB2 Location  Gag(78-86)   Gag Epitope Map
View variants at this location
Epitope LYNTVAVLY   Epitope Alignment
LYNTiAVLY   observed variant
Epitope Name LY9
Species (MHC/HLA human(A*29)

Variant Details

Showing 1 of 3 variants.

Variant ID.  4195
Epitope Seq.  LYNTVAVLY
Variant Seq.  LYNTiAVLY
Mutations V/I
Epitope Location V5I
HXB2 Location V82I
Mutation Type OV: observed variant
Method Other, Relative replication capacity assay
Note Longitudinal deep sequencing in Subject 9213 showed that the mutant LYNTiAVL corresponding to the position with the lowest h value, was the infecting strain (100%) until day 476, but was at 5.4% of the viral population by day 1543.


Ferguson2013a Andrew L. Ferguson, Jaclyn K. Mann, Saleha Omarjee, Thumbi Ndung'u, Bruce D Walker, and Arup K. Chakraborty. Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design. Immunity, 38(3):606-617, 21 Mar 2013. PubMed ID: 23521886. Show all entries for this paper.

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