HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 62099

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope KYRLKHIVW   Epitope Alignment
KYRLKHvVW   observed variant
Epitope Name KW9
Species (MHC/HLA human(A*24)

Variant Details

Showing 1 of 3 variants.

Variant ID.  4194
Epitope Seq.  KYRLKHIVW
Variant Seq.  KYRLKHvVW
Mutations I/V
Epitope Location I7V
HXB2 Location I34V
Mutation Type OV: observed variant
Method Sequence
Note Longitudinal deep sequencing in Subject 9213 showed that the mutant KYRLKHvVW corresponding to the position with the third lowest h value, appeared by day 1543 in 20.5% of the viral population, the rest being WT.


Ferguson2013a Andrew L. Ferguson, Jaclyn K. Mann, Saleha Omarjee, Thumbi Ndung'u, Bruce D Walker, and Arup K. Chakraborty. Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design. Immunity, 38(3):606-617, 21 Mar 2013. PubMed ID: 23521886. Show all entries for this paper.

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