HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61945

HXB2 Location  Gag(124-132)   Gag Epitope Map
View variants at this location
Epitope NSSKVSQNY   Epitope Alignment
sSSqVSQNY   susceptible form
Species (MHC/HLA human(A*01:01)

Variant Details

Showing 1 of 6 variants.

Variant ID.  4153
Epitope Seq.  NSSKVSQNY
Variant Seq.  sSSqVSQNY
Mutations N/S K/Q
Epitope Location N1S K4Q
HXB2 Location N124S K127Q
Mutation Type SF: susceptible form
Epitope Subtype A, D
Variant Subtype A, D
Method CD8 T-cell Elispot - IFNy, Other, Tetramer binding
Note 4/5 female A*0101+ patients responded to this novel variant of NSSKVSQNY, sSSqVSQNY, with a mean of 130 SFU/million cells.


Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.

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