Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 61945

HXB2 Location Gag(124-132) Gag Epitope Map
View variants at this location

Epitope

NSSKVSQNY

Epitope Alignment

Variants

hSnqVSQNY susceptible form

Species (MHC/HLA) human(A*01:01)

Variant Details

Showing 1 of 6 variants.

Variant ID.	`4151`
Epitope Seq.	`NSSKVSQNY`
Variant Seq.	`hSnqVSQNY`
Mutations	N/H S/N K/Q
Epitope Location	N1H S3N K4Q
HXB2 Location	N124H S126N K127Q
Mutation Type	SF: susceptible form
Epitope Subtype	A, D
Variant Subtype	A, D
Method	CD8 T-cell Elispot - IFNy, Other, Tetramer binding
Note	4/5 female A*0101+ patients responded to this variant of NSSKVSQNY, hSnqVSQNY, with a mean of 115 SFU/million cells.

References

Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.