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Displaying record number 61936

HXB2 Location Gag(146-155) Gag Epitope Map
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Epitope

{P}LSPRTLNAW

Epitope Alignment

Variants

{s}LSPRTLNAW observed variant

Epitope Name ISW9

Species (MHC/HLA) human(B*57)

Variant Details

Showing 1 of 3 variants.

Variant ID.	`4136`
Epitope Seq.	`{P}LSPRTLNAW`
Variant Seq.	`{s}LSPRTLNAW`
Mutations	P/S
Epitope Location	P1S
HXB2 Location	P146S
Mutation Type	OV: observed variant
Epitope Subtype	CRF01_AE
Variant Subtype	CRF01_AE
Method	Sequence
Note	Variant {s}LSPRTLNAW, at -1 position of the CRF01_AE ISW9 epitope was seen in donor patient N094 at 86%, 77% and 100%; 8, 20 and 42 mpd respectively. For recipient patient N107, this mutation was seen at 100% and 98% at months 42 and 52 post diagnosis.

References

Brener2015 Jacqui Brener, Astrid Gall, Rebecca Batorsky, Lynn Riddell, Soren Buus, Ellen Leitman, Paul Kellam, Todd Allen, Philip Goulder, and Philippa C. Matthews. Disease Progression Despite Protective HLA Expression in an HIV-Infected Transmission Pair. Retrovirology, 12:55, 2015. PubMed ID: 26123575. Show all entries for this paper.