HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(124-132)|| Gag Epitope Map
View variants at this location
|Epitope Name||NY9, p17NY9|
Showing all: 1 variant(s).
|Mutation Type||OV: observed variant
RCOK: replicative capacity is not abrogated
|Method||CTL suppression of replication, Intracellular cytokine staining, Tetramer binding|
|Note||Gag S126G, an HLA-A*1101-associated polymorphism is in the GagNY9 epitope, and did not accumulate in HLA-B*3501+ Japanese individuals. This mutation is selected by A*1101-restricted CTL and did not influence control of HIV-1 by B*3501-specific CTL.|
Murakoshi2018a Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, Takayuki Chikata, Nozomi Kuse, Hiroyuki Gatanaga, Sarah L. Rowland-Jones, Shinichi Oka, and Masafumi Takiguchi. Impact of a Single HLA-A*24:02-Associated Escape Mutation on the Detrimental Effect of HLA-B*35:01 in HIV-1 Control. EBioMedicine, 36:103-112, Oct 2018. PubMed ID: 30249546. Show all entries for this paper.