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Found 1 matching record:

Displaying record number 104

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNaVATL   susceptible form
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 4 variants.


Variant ID.  411
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNaVATL
Mutations T/A
Epitope Location T5A
HXB2 Location T81A
Mutation Type SF: susceptible form
Method Chromium-release assay
Note No variants were found in the patient, but this synthetic variant was tested against patient CTLs. The variant was recognized by CTLs and induced target specific lysis.

References

Harrer1998 T. Harrer, E. Harrer, P. Barbosa, F. Kaufmann, R. Wagner, S. Bruggemann, J. R. Kalden, M. Feinberg, R. P. Johnson, S. Buchbinder, and B. D. Walker. Recognition of Two Overlapping CTL Epitopes in HIV-1 p17 by CTL from a Long-Term Nonprogressing HIV-1-Infected Individual. J. Immunol., 161:4875-4881, 1998. PubMed ID: 9794421. Show all entries for this paper.


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