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Found 1 matching record:

Displaying record number 61878

HXB2 Location  Gag(198-205)   Gag Epitope Map
View variants at this location
Epitope MQMLKETI   Epitope Alignment
Variants
MQiLKETI   observed variant; susceptible form
Epitope Name Gag MI8
Species (MHC/HLA human(B*52:01)

Variant Details

Showing 1 of 2 variants.


Variant ID.  4087
Epitope Seq.  MQMLKETI
Variant Seq.  MQiLKETI
Mutations M/I
Epitope Location M3I
HXB2 Location M200I
Mutation Type OV: observed variant
SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Other
Note MQiLKETI, MI8-3I is a variant of B*5201-restricted WT epitope MQMLKETI. It was cross-recognized by MI8-specific CTL, and is found in 0.6% chronically HIV-1-infected Japanese patients and 1.2% of those who were B*5201+.

References

Murakoshi2019 Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Yu Zhang, Takayuki Chikata, Mohamed Ali Borghan, Hiroyuki Gatanaga, Shinichi Oka, Keiko Sakai, and Masafumi Takiguchi. Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication. J. Virol., 93(1), 1 Jan 2019. PubMed ID: 30333175. Show all entries for this paper.


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