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Displaying record number 61684

HXB2 Location Gag(11-31) Gag Epitope Map
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Epitope

GKLDAWEKIRLRPGGKKKYRL

Epitope Alignment

Variants

GKLDeWEKIRLRPGGKKKYRL non-susceptible form; susceptible form; subtype-specific susceptible form

Species (MHC/HLA) human

Variant Details

Showing 1 of 6 variants.

Variant ID.	`4083`
Epitope Seq.	`GKLDAWEKIRLRPGGKKKYRL`
Variant Seq.	`GKLDeWEKIRLRPGGKKKYRL`
Mutations	A/E
Epitope Location	A5E
HXB2 Location	A15E
Mutation Type	NSF: non-susceptible form SF: susceptible form SSF: subtype-specific susceptible form
Epitope Subtype	A1, D, M group
Variant Subtype	D
Method	CD8 T-cell Elispot - IFNy
Note	HIV ConD-specific OLP GKLDeWEKIRLRPGGKKKYRL was reactive in 19/20 subjects tested, 2377 sfu/10⁶ pbmc.

References

Mugaba2014 S. Mugaba, R. Nakiboneka, M. Nanyonjo, D. Bugembe-Lule, I. Kaddu, B. Nanteza, R. Tweyongyere, P. Kaleebu, and J. Serwanga. Group M Consensus Gag and Nef Peptides Are as Efficient at Detecting Clade A1 and D Cross-Subtype T-Cell Functions as Subtype-Specific Consensus Peptides. Vaccine, 32(30):3787-3795, 24 Jun 2014. PubMed ID: 24837770. Show all entries for this paper.