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Found 1 matching record:

Displaying record number 61684

HXB2 Location  Gag(11-31)   Gag Epitope Map
View variants at this location
Epitope GKLDAWEKIRLRPGGKKKYRL   Epitope Alignment
Variants
GKLDeWEKIRLRPGGKKKYRL   non-susceptible form; susceptible form; subtype-specific susceptible form
Species (MHC/HLA human

Variant Details

Showing 1 of 6 variants.


Variant ID.  4082
Epitope Seq.  GKLDAWEKIRLRPGGKKKYRL
Variant Seq.  GKLDeWEKIRLRPGGKKKYRL
Mutations A/E
Epitope Location A5E
HXB2 Location A15E
Mutation Type NSF: non-susceptible form
SF: susceptible form
SSF: subtype-specific susceptible form
Epitope Subtype A1, D, M group
Variant Subtype D
Method CD8 T-cell Elispot - IFNy
Note HIV ConD-specific OLP GKLDeWEKIRLRPGGKKKYRL was reactive in 19/20 subjects tested, 2377 sfu/106 pbmc.

References

Mugaba2014 S. Mugaba, R. Nakiboneka, M. Nanyonjo, D. Bugembe-Lule, I. Kaddu, B. Nanteza, R. Tweyongyere, P. Kaleebu, and J. Serwanga. Group M Consensus Gag and Nef Peptides Are as Efficient at Detecting Clade A1 and D Cross-Subtype T-Cell Functions as Subtype-Specific Consensus Peptides. Vaccine, 32(30):3787-3795, 24 Jun 2014. PubMed ID: 24837770. Show all entries for this paper.


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