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Displaying record number 61684

HXB2 Location Gag(11-31) Gag Epitope Map
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Epitope

GKLDAWEKIRLRPGGKKKYRL

Epitope Alignment

Variants

-----WEKIRLRPGG------ non-susceptible form; susceptible form

Species (MHC/HLA) human

Variant Details

Showing 1 of 6 variants.

Variant ID.	`4078`
Epitope Seq.	`GKLDAWEKIRLRPGGKKKYRL`
Variant Seq.	`-----WEKIRLRPGG------`
Mutations	G/- K/- K/- K/- Y/- K/- R/- L/- L/- D/- A/-
Epitope Location	G1- K16- K17- K18- Y19- K2- R20- L21- L3- D4- A5-
HXB2 Location	G11- K26- K27- K28- Y29- K12- R30- L31- L13- D14- A15-
Mutation Type	NSF: non-susceptible form SF: susceptible form
Epitope Subtype	A1, D, M group
Variant Subtype	A
Method	CD8 T-cell Elispot - IFNy
Note	HIV clone UG003 ConA- or ConD-specific truncated OLP variant -----WEKIRLRPGG------ was reactive in 9/10 subjects tested each, 1540 or 2225 sfu/10⁶ pbmc.

References

Mugaba2014 S. Mugaba, R. Nakiboneka, M. Nanyonjo, D. Bugembe-Lule, I. Kaddu, B. Nanteza, R. Tweyongyere, P. Kaleebu, and J. Serwanga. Group M Consensus Gag and Nef Peptides Are as Efficient at Detecting Clade A1 and D Cross-Subtype T-Cell Functions as Subtype-Specific Consensus Peptides. Vaccine, 32(30):3787-3795, 24 Jun 2014. PubMed ID: 24837770. Show all entries for this paper.