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Found 1 matching record:

Displaying record number 60269

HXB2 Location  Gag(1-20)   Gag Epitope Map
View variants at this location
Epitope MGARASVLSGGKLDAWEKIR   Epitope Alignment
Variants
MGARASVLSGGKLDA-----   non-susceptible form
Species (MHC/HLA human

Variant Details

Showing 1 of 3 variants.


Variant ID.  4077
Epitope Seq.  MGARASVLSGGKLDAWEKIR
Variant Seq.  MGARASVLSGGKLDA-----
Mutations W/- E/- K/- I/- R/-
Epitope Location W16- E17- K18- I19- R20-
HXB2 Location W16- E17- K18- I19- R20-
Mutation Type NSF: non-susceptible form
Epitope Subtype A1, D, M group
Variant Subtype M group
Method CD8 T-cell Elispot - IFNy
Note ConM-specific truncated peptide MGARASVLSGGKLDA----- was non-reactive in 100% subjects (15/15) tested. The ConA, ConM peptide, MGARASVLSGGKLDAWEKIR did not elicit any response in the subjects tested either.

References

Mugaba2014 S. Mugaba, R. Nakiboneka, M. Nanyonjo, D. Bugembe-Lule, I. Kaddu, B. Nanteza, R. Tweyongyere, P. Kaleebu, and J. Serwanga. Group M Consensus Gag and Nef Peptides Are as Efficient at Detecting Clade A1 and D Cross-Subtype T-Cell Functions as Subtype-Specific Consensus Peptides. Vaccine, 32(30):3787-3795, 24 Jun 2014. PubMed ID: 24837770. Show all entries for this paper.


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