HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(161-172) | Gag Epitope Map
View variants at this location |
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| Epitope |
EKAFSPEVIPMF
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | Gag-KF11 | |||||
| Species (MHC/HLA) | human(B*57:03, B*58:01) | |||||
Showing 1 of 5 variants.
| Variant ID. | 4061 |
|---|---|
| Epitope Seq. | EKAFSPEVIPMF |
| Variant Seq. | EKsFSPEVIPMF |
| Mutations | A/S |
| Epitope Location | A3S |
| HXB2 Location | A163S |
| Mutation Type | A: HLA association |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | CD8 T-cell Elispot - IFNy, Computer prediction |
| Note | HLA-associated escape, EKsFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801. |
Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.