HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61675

HXB2 Location  Gag(161-172)   Gag Epitope Map
View variants at this location
Epitope EKAFSPEVIPMF   Epitope Alignment
dKAFSPEVIPMF   HLA association
Epitope Name Gag-KF11
Species (MHC/HLA human(B*57:03, B*58:01)

Variant Details

Showing 1 of 5 variants.

Variant ID.  4060
Variant Seq.  dKAFSPEVIPMF
Mutations E/D
Epitope Location E1D
HXB2 Location E161D
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, dKAFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.

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