HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61674

HXB2 Location  Gag(146-155)   Gag Epitope Map
View variants at this location
Epitope AISPRTLNAW   Epitope Alignment
pISPRTLNAW   HLA association
Epitope Name Gag-IW9
Species (MHC/HLA human(B*57:02, B*57:03, B*58:01)

Variant Details

Showing 1 of 3 variants.

Variant ID.  4057
Epitope Seq.  AISPRTLNAW
Variant Seq.  pISPRTLNAW
Mutations A/P
Epitope Location A1P
HXB2 Location A146P
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, pISPRTLNAW, was associated more strongly with HLAs-B*5702 and B*5703 than with HLA-B*5801.


Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.

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