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Displaying record number 59429

HXB2 Location Gag(166-175) Gag Epitope Map
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Epitope

PEVIPMFSAL

Epitope Alignment

Variants

PEVIPMFtAL observed variant

Epitope Name Gag166-175

Species (MHC/HLA) human(C*03:04)

Variant Details

Showing 1 of 3 variants.

Variant ID.	`4042`
Epitope Seq.	`PEVIPMFSAL`
Variant Seq.	`PEVIPMFtAL`
Mutations	S/T
Epitope Location	S8T
HXB2 Location	S173T
Mutation Type	OV: observed variant
Method	Sequence
Note	The S173T variant at position 8, PEVIPMFtAL (34-8T), was present at a frequency of 39.1%.

References

vanTeijlingen2014 Nienke H. van Teijlingen, Angelique Hölzemer, Christian Körner, Wilfredo F. García-Beltrán, Jamie L. Schafer, Lena Fadda, Todd J. Suscovich, Christian Brander, Mary Carrington, David T Evans, Debbie van Baarle, and Marcus Altfeld. Sequence Variations in HIV-1 p24 Gag-Derived Epitopes Can Alter Binding of KIR2DL2 to HLA-C*03:04 and Modulate Primary Natural Killer Cell Function. AIDS, 28(10):1399-1408, 19 Jun 2014. PubMed ID: 24785948. Show all entries for this paper.