HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59380

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
KAFSPEiIPMF{t}   observed variant
Epitope Name KF11
Species (MHC/HLA human(B*57:01, B*57:03)

Variant Details

Showing 1 of 14 variants.

Variant ID.  4031
Epitope Seq.  KAFSPEVIPMF{S}
Variant Seq.  KAFSPEiIPMF{t}
Mutations S/T V/I
Epitope Location S+1T V7I
HXB2 Location S173T V168I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 7% B*5703+ and 0% B*5703- subjects of the Barbados cohort carried variant KAFSPEiIPMF{t} in the +1 position.


Payne2014 R. P. Payne, S. Branch, H Kløverpris, P. C. Matthews, C. K. Koofhethile, T. Strong, E. Adland, E. Leitman, J. Frater, T. Ndung'u, E. Hunter, R. Haubrich, B. Mothe, A. Edwards, L. Riddell, F. Chen, P. R. Harrigan, Z. L. Brumme, S. Mallal, M. John, J. P. Jooste, R. Shapiro, S. G. Deeks, B. D. Walker, C. Brander, C. Landis, J. M. Carlson, J. G. Prado, and P. J. R. Goulder. Differential Escape Patterns within the Dominant HLA-B*57:03-Restricted HIV Gag Epitope Reflect Distinct Clade-Specific Functional Constraints. J. Virol., 88(9):4668-4678, May 2014. PubMed ID: 24501417. Show all entries for this paper.

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