Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 61530

HXB2 Location Gag(39-46) Gag Epitope Map
View variants at this location

Epitope

RELERFAV

Epitope Alignment

Variants

RELERFAl subtype-specific susceptible form

Epitope Name Gag RV8

Species (MHC/HLA) human(B*40:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`3932`
Epitope Seq.	`RELERFAV`
Variant Seq.	`RELERFAl`
Mutations	V/L
Epitope Location	V8L
HXB2 Location	V46L
Mutation Type	SSF: subtype-specific susceptible form
Epitope Subtype	B
Variant Subtype	CRF01_AE
Method	CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Sequence
Note	A/E clade epitope RELERFAl was found in 17/26 A/E patients of the KI cohort, though it was found in 111/1644 B virus and 217/315 clade A/E virus sequences in the Los Alamos HIV-1 database. It was recognized by CTL from clade A/E-infected patient KI-388 which had been elicited by consensus clade B RV8.

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.