HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61528

HXB2 Location  Gag(31-41)   Gag Epitope Map
View variants at this location
Epitope LKHIVWASREL   Epitope Alignment
mKHlVWASREL   subtype-specific susceptible form
Epitope Name Gag LL11
Species (MHC/HLA human(A*02:06)

Variant Details

Showing all: 1 variant(s).

Variant ID.  3930
Variant Seq.  mKHlVWASREL
Mutations L/M I/L
Epitope Location L1M I4L
HXB2 Location L31M I34L
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype CRF01_AE
Method Intracellular cytokine staining, Sequence
Note A/E clade epitope mKHlVWASREL was found in 14/26 A/E patients of the KI cohort, though it was found in no B virus and 147/315 clade A/E virus sequences in the Los Alamos HIV-1 database. It was not recognized by CTL from clade A/E-infected patient KI-388 which had been elicited by consensus clade B LL11.


Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.

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