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Found 1 matching record:

Displaying record number 61471

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTiAvL   escape documented in this paper
Epitope Name SL9
Species (MHC/HLA human(A*02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3909
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiAvL
Mutations Y/F V/I T/V
Epitope Location Y3F V6I T8V
HXB2 Location Y79F V82I T84V
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Intracellular cytokine staining, Other
Note Triple mutant, SLfNTiAvL-HIV when infected into LRA-treated CD4+ T cells, was not recognizable by non-mutant-SL9-recognizing CTL.

References

Jones2016 R. Brad Jones, Stefanie Mueller, Rachel O'Connor, Katherine Rimpel, Derek D. Sloan, Dan Karel, Hing C. Wong, Emily K. Jeng, Allison S. Thomas, James B. Whitney, So-Yon Lim, Colin Kovacs, Erika Benko, Sara Karandish, Szu-Han Huang, Maria J. Buzon, Mathias Lichterfeld, Alivelu Irrinki, Jeffrey P. Murry, Angela Tsai, Helen Yu, Romas Geleziunas, Alicja Trocha, Mario A. Ostrowski, Darrell J. Irvine, and Bruce D. Walker. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog., 12(4):e1005545, Apr 2016. PubMed ID: 27082643. Show all entries for this paper.


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