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Displaying record number 61462

HXB2 Location Gag(92-101) Gag Epitope Map
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Epitope

IEVKDTKEAL

Epitope Alignment

Variants

{HQr}IaVKDTKEAL{DKLEE} observed variant

Epitope Name IL10-B40

Species (MHC/HLA) human

Variant Details

Showing 1 of 8 variants.

Variant ID.	`3894`
Epitope Seq.	`{HQK}IEVKDTKEAL{DKLEE}`
Variant Seq.	`{HQr}IaVKDTKEAL{DKLEE}`
Mutations	K/R E/A
Epitope Location	K-1R E2A
HXB2 Location	K91R E93A
Mutation Type	OV: observed variant
Epitope Subtype	CRF01_AE
Variant Subtype	CRF01_AE
Method	Other, Sequence
Note	2/12 HIV-1 sequences in Subject 12 carried K91R, E93A variations within epitope IL10 at 1 year post-infection, IaVKDTKEAL, with the upstream flanking mutation at -1 position.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.