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Found 1 matching record:

Displaying record number 61462

HXB2 Location  Gag(92-101)   Gag Epitope Map
View variants at this location
Epitope IEVKDTKEAL   Epitope Alignment
Variants
{HQr}IgVKDTKEAL{DKLEE}   observed variant
Epitope Name IL10-B40
Species (MHC/HLA human

Variant Details

Showing 1 of 8 variants.


Variant ID.  3893
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IgVKDTKEAL{DKLEE}
Mutations K/R E/G
Epitope Location K-1R E2G
HXB2 Location K91R E93G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/12 HIV-1 sequences in Subject 12 carried K91R, E93G variations within epitope IL10 at 1 year post-infection, IgVKDTKEAL, with the upstream flanking mutation at -1 position.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


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