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Found 1 matching record:

Displaying record number 1819

HXB2 Location  Gag(19-27)   Gag Epitope Map
View variants at this location
Epitope IRLRPGGKK   Epitope Alignment
Variants
IRLRPGGsK   inferred escape
Epitope Name IK9
Species (MHC/HLA human(B27)

Variant Details

Showing 1 of 5 variants.


Variant ID.  389
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRLRPGGsK
Mutations K/S
Epitope Location K8S
HXB2 Location K26S
Mutation Type IE: inferred escape
Note Variant found in one B27 positive child in 7/8 clones, and in its B27 positive mother in 9/10 clones.

References

Goulder2001c P. J. Goulder, C. Brander, Y. Tang, C. Tremblay, R. A. Colbert, M. M. Addo, E. S. Rosenberg, T. Nguyen, R. Allen, A. Trocha, M. Altfeld, S. He, M. Bunce, R. Funkhouser, S. I. Pelton, S. K. Burchett, K. McIntosh, B. T. Korber, and B. D. Walker. Evolution and transmission of stable CTL escape mutations in HIV infection. Nature, 412(6844):334-8, 19 Jul 2001. PubMed ID: 11460164. Show all entries for this paper.


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