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Displaying record number 1819

HXB2 Location Gag(19-27) Gag Epitope Map
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Epitope

IRLRPGGKK

Epitope Alignment

Variants

IRLgPGGsK inferred escape

Epitope Name IK9

Species (MHC/HLA) human(B27)

Variant Details

Showing 1 of 5 variants.

Variant ID.	`388`
Epitope Seq.	`IRLRPGGKK`
Variant Seq.	`IRLgPGGsK`
Mutations	R/G K/S
Epitope Location	R4G K8S
HXB2 Location	R22G K26S
Mutation Type	IE: inferred escape
Note	Author tabulates this variant found in one B27 positive child in 1/8 clones, and in its B27 positive mother in 1/10 clones as an escape variant.

References

Goulder2001c P. J. Goulder, C. Brander, Y. Tang, C. Tremblay, R. A. Colbert, M. M. Addo, E. S. Rosenberg, T. Nguyen, R. Allen, A. Trocha, M. Altfeld, S. He, M. Bunce, R. Funkhouser, S. I. Pelton, S. K. Burchett, K. McIntosh, B. T. Korber, and B. D. Walker. Evolution and transmission of stable CTL escape mutations in HIV infection. Nature, 412(6844):334-8, 19 Jul 2001. PubMed ID: 11460164. Show all entries for this paper.