HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61246

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNMML   Epitope Alignment
TPQDLNtML   HLA association; observed variant
Epitope Name TL9M7
Species (MHC/HLA human(B*42:01, B*81:01)

Variant Details

Showing 1 of 7 variants.

Variant ID.  3766
Epitope Seq.  TPQDLNMML
Variant Seq.  TPQDLNtML
Mutations M/T
Epitope Location M7T
HXB2 Location M186T
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPQDLNtML, is present in 2.5% of B*42-/B*81- subjects and 16.7% of B*42+ subjects.


Geldmacher2009 Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup. Minor Viral and Host Genetic Polymorphisms Can Dramatically Impact the Biologic Outcome of an Epitope-Specific CD8 T-Cell Response. Blood, 114(8):1553-1562, 20 Aug 2009. PubMed ID: 19542300. Show all entries for this paper.

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