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Found 1 matching record:

Displaying record number 61246

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNMML   Epitope Alignment
Variants
TPgDLNMML   HLA association; observed variant
Epitope Name TL9M7
Species (MHC/HLA human(B*42:01, B*81:01)

Variant Details

Showing 1 of 7 variants.


Variant ID.  3765
Epitope Seq.  TPQDLNMML
Variant Seq.  TPgDLNMML
Mutations Q/G
Epitope Location Q3G
HXB2 Location Q182G
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPgDLNMML, is present in 5% of B*42-/B*81- and 11.1% of the B*81+ subjects.

References

Geldmacher2009 Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup. Minor Viral and Host Genetic Polymorphisms Can Dramatically Impact the Biologic Outcome of an Epitope-Specific CD8 T-Cell Response. Blood, 114(8):1553-1562, 20 Aug 2009. PubMed ID: 19542300. Show all entries for this paper.


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