HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61246

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNMML   Epitope Alignment
iPhDLNMML   HLA association; observed variant
Epitope Name TL9M7
Species (MHC/HLA human(B*42:01, B*81:01)

Variant Details

Showing 1 of 7 variants.

Variant ID.  3761
Epitope Seq.  TPQDLNMML
Variant Seq.  iPhDLNMML
Mutations T/I Q/H
Epitope Location T1I Q3H
HXB2 Location T180I Q182H
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, iPhDLNMML, is present in 2.5% of B*42-/B*81- subjects.


Geldmacher2009 Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup. Minor Viral and Host Genetic Polymorphisms Can Dramatically Impact the Biologic Outcome of an Epitope-Specific CD8 T-Cell Response. Blood, 114(8):1553-1562, 20 Aug 2009. PubMed ID: 19542300. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health